Matti Aapro SIOG Executive Director – Disability N Normal Aging
Almost all the changes associated with aging lead to reduced function. However, the population is characterized by high variability in the rate of functional decline, both between individuals and within individuals. Three different trajectories of aging have been described. No aging with disease and normal aging with disability No disability No successful aging with a disability minimal heterogeneity of the aging process has practical consequences for the evaluation of older cancer patients: patients need individualized assessments for determine their biological age. Biological age is estimated to reflect the life expectancy of a person remaining and functional reserves. This will influence treatment decisions and predict tolerance of treatment. There is no simple way to evaluate the biological age, and the best tool available today is a comprehensive geriatric assessment described in a separate chapter in this book. Traditionally, in gerontology and geriatrics, natural age-dependent changes in the structure or function of organs were distinguished from age-related pathologies. This distinction is perhaps less useful from a practical point of view. In addition, normal age-dependent changes are believed to be associated with the prevalence of related diseases, and disease in the organs and the aging process will exert synergistic effects on the other.
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